JEE Main 2022 — Chemistry In Everyday Life Question with Solution
From: JEE Main 2022 (Online) 28th July Evening Shift
Question
Two statements in respect of drug-enzyme interaction are given below
Statement I : Action of an enzyme can be blocked only when an inhibitor blocks the active site of the enzyme.
Statement II : An inhibitor can form a strong covalent bond with the enzyme.
In the light of the above statements, choose the correct answer from the options given below
Choose an option
Show full solutionCorrect option: D
Step-by-step explanation
Let's analyze both statements:
Statement I: Action of an enzyme can be blocked only when an inhibitor blocks the active site of the enzyme. This statement is false because enzyme inhibition can occur in more than one way. Besides competitive inhibition (where the inhibitor binds to the active site), there are other types such as non-competitive and uncompetitive inhibition, where the inhibitor can bind elsewhere on the enzyme, altering its function.
Statement II: An inhibitor can form a strong covalent bond with the enzyme. This statement is true. Some inhibitors, known as irreversible inhibitors, form strong covalent bonds with the enzyme, permanently inactivating it.
So the correct answer is:
Option D: Statement I is false but Statement II is true.
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This is a previous-year question from JEE Main 2022, covering the Chemistry In Everyday Life chapter of Chemistry. PrepSharp catalogues every PYQ from JEE Main with a verified answer key and step-by-step solution prepared by IIT alumni — so you can search by chapter, topic or year and revise efficiently.